1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity associated with bortezomib, a proteasome inhibitor Employed in the therapy of numerous myeloma. Its synthesis or research is crucial for making sure the purity and basic safety in the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug Utilized in the cure of prostate cancer by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-10-one): A essential compound inside the synthesis of imatinib, a drug that targets specific sorts of cancer, such as Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats different cancers such as breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They are intermediates in the synthesis of gemcitabine, an anti-cancer drug. Their review is vital for optimizing the output procedure and making sure large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is utilized to deal with breast most cancers, and these intermediates are involved in its manufacturing.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist 16-dien-3-ol used in the procedure of breast cancer. A variety of intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug helpful in treating cancers such as ovarian, breast, and lung most cancers.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the treatment method of colorectal most cancers and compact mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is 5-deoxy- involved in the synthesis of adamantane derivatives, that have different programs, which include antiviral Attributes.
Vildagliptin Intermediates: Utilized in the creation of vildagliptin, an oral drug for kind two diabetes that inhibits the enzyme DPP-4 to control blood sugar levels.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with the synthesis of various gluconic acid derivatives, that happen to be Employed in food items, pharmaceutical, and industrial apps.
Canagliflozin Intermediate two: A precursor from the synthesis of canagliflozin, a medication made use of to deal with form 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).